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Image Search Results
Journal: bioRxiv
Article Title: Hemodynamic Analysis of a Repaired Ascending Aorta with Preserved Aortic Root
doi: 10.64898/2026.01.28.702307
Figure Lengend Snippet: Overall workflow for creating and analyzing a patient-specific FEA model of the thoracic aorta with the aortic valve, including boundary condition configuration and material subdomains for CFD and FSI analyses. (a) Pipeline to extract aortic vessel lumen from a patient’s CTA images using SimVascular and MeshMixer (Autodesk, Inc.), including path planning, model lofting, and meshing [ , ]. (b) Steps to segment a patient-specific aortic valve, fully integrated with the surrounding aortic vessel wall. The vessel wall is created by extruding the lumen’s outer surface by 1.5 mm using MeshMixer. (c) Cross-sectional views of the segmented aortic valve, viewed from the aortic side, for the three cases studied: preoperative (preop) and postoperative (postop) models of an ATAA patient with dilated STJ, and a control subject. (d) Fluid domain with relevant boundary conditions comprising a prescribed inflow profile at the inlet (A) and three-element Windkessel networks at each outlet (B-E). (e) Boundary conditions for the solid domain accounting for external tissue support on the outer wall, while the inflow and outflow annular walls are fixed. The highlighted gray subdomain corresponds to the reconstructed STJ graft, where the properties of Dacron material were applied to assess material sensitivity. (f) Laplacian-Dirichlet solution field ( ϕ ) used to construct valvular subdomains to allow a smooth transition in the material parameters between the leaflet belly and leaflet attachment edge. (g) Schematics for morphological analysis of (left) aorta partitioned into segments based on vessel centerline and (right) aortic root, characterized using length measurements between (top) sinus to commissure and (bottom) commissure to commissure. FEA: finite element analysis; CFD: computational fluid dynamics; FSI: fluid-structure interaction; CTA: computed tomography angiography; ATAA: ascending thoracic aortic aneurysm; STJ: sino-tubular junction; RCC: right coronary cusp; LCC: left coronary cusp; NCC: non-coronary cusp.
Article Snippet: Surface distortions due to intersections near the branch vessels after extrusion are resolved by local
Techniques: Control, Construct, Computed Tomography